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论文摘要

口腔黏膜溃疡损害出现短暂自愈的朗格汉斯细胞组织细胞增生症1例

Oral mucosal lesions with transient self-healing of Langerhans cell histiocytosis: a case report

作者:张晓玲, 薛宁宁, 阮敏慧, 曾昕

Author:Zhang Xiaoling, Xue Ningning, Ruan Minhui, Zeng Xin.

收稿日期:2023-03-21          年卷(期)页码:2023,41(5):592-592-598

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:朗格汉斯细胞组织细胞增生症,自愈,口腔黏膜溃疡,诊断,

Key words:Langerhans cell histiocytosis,self-healing,oral ulcer,diagnosis,

基金项目:国家自然科学基金(U19A2005);中国医学科学院临床与转化医学研究基金(2020-I2M-C&T-A-023)

中文摘要

朗格汉斯细胞组织细胞增生症(LCH)是一组原因不明的朗格汉斯细胞组织细胞异常增殖聚集疾病,多发于儿童。LCH分为勒-雪病、汉-许-克病、嗜酸性肉芽肿、先天性自愈性朗格汉斯细胞组织细胞增生症4种临床类型。病损可累及单器官或全身多处器官,临床表现根据累及器官不同而不同,皮肤黏膜可为LCH的首发部位。根据受累器官,LCH有不同的治疗方法,包括手术、放疗、联合化疗等。本文报道1例口腔黏膜溃疡性病损曾经出现短暂自愈的LCH,旨在为罕见病LCH的临床诊疗提供更多参考信息。

英文摘要

Langerhans cell histiocytosis (LCH) is a group of unexplainable abnormal proliferation and aggregation of Langerhans cell. LCH can be classified into four clinical variants: Letterer-Siwe disease, Hand-Schüller-Christian disease, eosinophilic granuloma, and congenital self-healing LCH. LCH is most prevalent in children. Lesions can be localized in a single system or multiple organs, and clinical manifestations vary depending on the affected organs. The skin and mucocutaneous tissues are the starting point of the affected tissue. This study presents a LCH case characterized by transient self-healing. This case can further provide references for the clinical diagnosis and treatment of LCH.

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