The development of ceramic materials, bonding techniques, new technology and issues of amalgam safety has led to widely using of all-ceramic inlays in dental restoration. Clinical studies have been carried out various evaluation techniques to assess the clinical performance of all-ceramic inlays. The major problems associated with ceramic inlay therapy appear to be fracture, hypersensitivity, degree of fit, maintenance of marginal integrity, microleakage, bond failures and cement wear. However, when compared with other forms of aesthetic intra-coronal restorations, ceramic inlays perform well. In this paper, recent clinical study articles were summarized and a review of the current state of knowledge regarding the clinical problems and survival statistics of ceramic
inlays was presented.