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论文摘要

Wnt 和Notch 信号通路及其与口腔鳞状细胞癌的关系

Crosstalk between Wnt and Notch signaling pathways and their relationships with o

作者:庞宝兴综述 金晓明审校

Author:PANG Bao -xing, JIN Xiao -ming

收稿日期:2008-12-09          年卷(期)页码:2009,36(3):341-343

期刊名称:国际口腔医学杂志

Journal Name:International Journal of Stomatology

关键字:Wnt,Notch,鳞状细胞癌,交互作用,

Key words:Wnt, Notch, squamous cell carcinoma, crosstalk,

基金项目:

中文摘要

Wnt 和Notch 信号通路是两条与肿瘤发生发展密切相关的信号转导通路,两者通过广泛密切的交互作用共同协调机体的生命活动。下面就Wnt 和Notch 信号通路及其在肿瘤发生发展中的交互作用以及与口腔鳞状细胞癌的关系作一综述。

英文摘要

Wnt and Notch signaling pathways have long been regarded as the signaling pathways playing critical roles in the tumorigenesis and progression of various kinds of human cancers. This article reviewed the crosstalk between Wnt and Notch signaling pathways, particularly focusing on their relationship with oral squamous cell carcinoma.

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