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论文摘要

RhoC 蛋白与涎腺肿瘤的关系

Association between RhoC and salivary gland tumor

作者:陆莉芳综述 胡济安审校

Author:LU Li-fang, HU Ji-an

收稿日期:2007-01-05          年卷(期)页码:2008,35(2):179-181

期刊名称:国际口腔医学杂志

Journal Name:International Journal of Stomatology

关键字:RhoC,肿瘤,侵袭,转移,涎腺肿瘤,

Key words:RhoC, tumor, invasion, metastasis, salivary glands tumor,

基金项目:

中文摘要

RhoC 蛋白GTP 酶是Ras 超家族小分子量G 蛋白成员。近来许多研究表明,RhoC 蛋白参与了恶性肿瘤的发生和发展。同时,RhoC 蛋白的过量表达与恶性肿瘤的侵袭转移密切相关。笔者在回顾国内外RhoC 蛋白研究的基础上,进一步探讨RhoC 蛋白与涎腺肿瘤的关系。

英文摘要

RhoC GTPase is a member of low molecular weight proteins belonging to the Ras superfamily. Recently many researches have demonstrated that RhoC played a role in genesis and development of malignant tumor, and overexpression of RhoC was reported to correlate with clinical cancer metastasis. Based on the studies concerning RhoC at home and abroad, we will further discuss the relation between RhoC and the tumor of salivary glands in this review.

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