期刊导航

论文摘要

牙周炎和趋化因子的研究新进展

New progr ess of per iodontitis and chemokines

作者:张浙丹,孙红英,

Author:ZHANG Zhe - dan, SUN Hong- ying.

收稿日期:          年卷(期)页码:2007,34(06):424-426

期刊名称:国际口腔医学杂志

Journal Name:International Journal of Stomatology

关键字:牙周炎,趋化因子,免疫机制,

Key words:periodontitis, chemokines, immune mechanism,

基金项目:

中文摘要

趋化因子(chemokines)是一类一级结构相似,对白细胞具有化学趋化作用等多种生物学效应的小分子蛋 白,在机体的防御和炎症反应等方面起着重要的调节作用。近年来许多研究发现,趋化因子在牙周炎的免疫发 病机制中发挥着重要作用。深入研究趋化因子和牙周炎的关系,对牙周炎的预防、诊断、治疗以及治疗后疗效 监测有重要意义。

英文摘要

The chemokines are a kind of small proteins with similar primary structures, which have various biological effect, mostly include chemotaxis of leukocyte, and play a significant regulating effect on the defense and the inflammatory reaction of the body. In recent years, a lot of researches have found that the chemokines play an important role in the immunopathogenesis of periodontitis. Therefore it is important to study the relation of chemokines and periodontitis for prevention, diagnosis, treatment and monitoring of curative effect of periodontitis.

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