期刊导航

论文摘要

免疫毒素在治疗口腔医学相关疾病中的应用

Application of immunotoxin in treatment of oral diseases

作者:张媛媛,陈谦明,林梅,

Author:ZHANG Yuan-yuan, CHEN Qian-ming, LIN Mei.

收稿日期:          年卷(期)页码:2007,34(04):278-280

期刊名称:国际口腔医学杂志

Journal Name:International Journal of Stomatology

关键字:免疫毒素,靶向治疗,头颈部肿瘤,

Key words:immunotoxin, target therapy, head and neck cancer,

基金项目:

中文摘要

免疫毒素是近年来新兴的一种特异性靶向治疗药物,由毒素蛋白和载体两部分构成。由于免疫毒素能高效、特异地杀伤靶细胞,目前已被应用于自身免疫性疾病、人类免疫缺陷病毒感染和肿瘤等多种疾病的靶向治疗和临床研究。本文主要综述了免疫毒素在口腔相关疾病生物治疗中应用的研究进展。

英文摘要

Immunotoxin is a novel class of targeted agents in recent years, which is composed of toxin fragment and antibody or cytokine. Because immunotoxin has the ability of high efficiently and specifically killing certain target cells, it has been used in curing a variety of disease, such as autoimmune disease, human immunodeficiency vinuses infection, and tumor. The development situation and application prospect of immunotoxin therapy in oral disease are reviewed in this paper.

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