Objective To evaluate the curative effects and safety evaluation of “Bushenguchiwan” recipe to the patients with “kidney deficiency and hyperfire” periodontitis. M ethods Eighty eight patients with“kidney deficiency and hyperfire”periodontitis, after scaling and root planning(SR P), were random ly divided into two groups, the test group were given “Bushenguchiwan” treatment, while the control group were given“Zhibaidihuangwan” treatm ent. Three m onths later, clinical indexes of periodontitis and the sym ptom s of traditional Chinese m edicine were evaluated. R esults There was no statistical significance on effective power of“kidney deficiency and hyperfire” periodontitis, and on the im provem ent of “kidney deficiency and hyperfire” symptoms in test and control group. Im ageology data showed that both of them could increase the dense of alveolar bone, but no statistical significance on difference exsisted; There was also no statistical significance on the incidence of adverse effect. C onclusion “Bushenguchiwan ”recipe is an effective and safe drug to treat“kidney deficiency and hyperfire”periodontitis, when on the bond of SR P.