We recently showed that adiponectin, an adipocyte derived cytokine, may function as a type Ⅱ diabetes protective factor. It had an effect of lowering blood glucose, increasing insulin sensitivity, anti-inflammatory, anti-atherosclerosis and regulating the bone metabolism. Periodontitis is considered as the sixth complication of diabetes. Some researches indicated that there lies a close relationship between periodontitis and diabetes, which often influence each other. The interaction of adiponectin and periodontitis is not clear. In this review, in order to acquire a new therapy of periodontitis in the future, the influence of adiponectin on type Ⅱ diabetes patients with periodontitis will be discussed.
