Silicone rubber is widely used in oral maxillofacial prosthesis and denture soft lining, because of its good physical, chemical, and biological properties. The low toxicity and surface porosity of silicone rubber provide a good condition for the proliferation of bacteria in oral environment. The adherence of bacteria, especially Candida albicans, can accelerate the aging and coloration of the material, affecting the esthetics and lowing the useful life of material, even cause denture stomatitis. So the research of antimicrobial effect of silicone rubber is one of the focuses in recent years. This paper summarized the current progress on the antimicrobial effect of denture soft liner and maxillofacial prosthesis silicone rubber.
