Traditional dentin water wet-bonding technique has been advocated by many scientists, but the surface wetness is difficult to control, the excess water will induce suboptimal polymerization of those adhesives, phase separation and nanolekage, which will influence the longevity of resin-dentin bonds. Recent studies have put forward a new concept which is dentin ethanol wet-bonding, this technique can increase in bond strength and durability. This review is focus on the principle of ethanol wet-bonding, its surface treatment methods and the research progress on it.