Although current root canal therapy offers a high success rate for many teeth with pulp diseases, there are still many post-treatment complications. Due to the development of life science such as molecular biology, cell biology, and developmental biology, it is possible that the pulp treatment approaches change from traditional obturation therapy to biological treatment. This review presents recent progresses in dental pulp reconstruction, including odontoblast regeneration, pulp revascularization, never regeneration and scaffold implantation.
