Objective To determine the effects, in economic aspect of clinical effects by porcelain fused-to-metal restoration made from Ni-Cr alloy or precious alloy during tooth defect or denture defect therapy. Methods A search for the objective articles was performed from the following database: CNKI, CBM and VP. RevMan software was applied to conduct meta-analysis. The clinical effects and economical analysis were studied. Results Twelve articles met the final selection criteria. The significant differences were found in the marginal color, gingivitis, damage, marginal fit the C/E of the precious alloy group was respectively 1 645.38 yuan, 1 588.79 yuan, 1 524.79 yuan, 2 201.95 yuan more than that of the Ni-Cr alloy group. Conclusion In clinical effects and biological safety aspect, the precious alloy is superior to Ni-Cr alloy. However, in economical aspect, the Ni-Cr alloy is to superior previous alloy.
