The favorable adhesion between the tooth and the resin adhesive was the crucial part in the adhesive domain. There were many influencing factors that affected the interface integrity, such as the disadvantages of the polymerization shrinkage and dissolution of the adhesive, the treatment of the tooth, the clinical manipulation and the host factor, resulting the failure of adhesive interface, microleakage and instability. It has been the research orientation about improving the bonding quality and durability of the resin-dentin adhesion. In this review, we summarized the influencing factors of the bond strength of resin adhesive.
