光学相干断层成像术对人牙窝沟釉质早期龋变深度的测量
Measurement of the depth of initial caries on the occlusal surface by optical coherence tomography
作者：靳淑凤，代晓华，姚晖，姚晓天，李燕妮，万木森，连小丽，梁雨
Author：JIN Shu-feng1, DAI Xiao-hua1, YAO Hui1, YAO Xiao-tian2, LI Yan-ni1, WAN Mu-sen2, LIAN Xiao-li1, LIANG Yu2.
收稿日期： 年卷（期）页码：2010,37(6):637-640
期刊名称：国际口腔医学杂志
Journal Name：International Journal of Stomatology
关键字：光学相干断层成像技术,偏光显微镜,龋病诊断, 牙合面龋,
Key words：optical coherence tomography, polarized light microscope, caries diagnosis, occlusal caries,
基金项目：
中文摘要
目的探讨光学相干断层成像技术（OCT）检测离体牙面窝沟釉质早期人工龋变深度的准确性和可行性。方法将7 颗因正畸治疗需要拔除的人前磨牙随机分成脱矿及脱矿-再矿化2 组，面开窗3 mm×4 mm。将脱矿组放入脱矿液中制备人工脱矿模型；将脱矿-再矿化组交替放入脱矿液和再矿化液制备人工龋模型。分别对上述2 组牙齿样本进行OCT 扫描，测得龋变深度；在牙齿样本OCT 扫描的相应部位制备磨片，测量偏光显微镜下龋变的深度。结果除了脱矿7 天的样本外，其余样本2 种检测方法测得的龋变深度差异无统计学意义（P>0.05），OCT 检测的龋变深度与偏光显微镜检测结果基本相符。结论OCT 作为一种无创的检测方法，可以对釉质窝沟早期人工龋清晰成像，并可进行龋变深度的量化分析，提示其在窝沟早期龋的临床诊断中具有应用潜能。
英文摘要
Objective To investigate the accuracy and feasibility of optical coherence tomography（OCT） in detecting early artificial caries on molar occlusal surfaces. Methods 7 extracted human’s premolars were divided into two groups（a demineralization group and a de- and remineralization group） in random. Each tooth was varnished with nail oil except for a window of 3 mm×4 mm on the occlusal surface. The teeth of demineralization group and de- and remineralization group were exposed into acid and pH cycling separately to create artificial carious of varying severity. The depth of artificial carious lesions was acquired from OCT images, while the histological images were acquired at the same scanning path of OCT images. Results The depth of artificial caries of all samples except the tooth demineralized 7 days be detected by OCT showed agreement with polarized microscopy（P>0.05）. Conclusion OCT is a noninvasive technology of caries detection. It can acquire images of occlusal caries and quantify lesion depth. That suggested the OCT has the potential of clinical diagnosis for the early carious lesion.
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