单核细胞趋化蛋白-1 和细胞间黏附分子-1 与动脉粥样硬化和牙周病的关系
Relation of monocyte chemoattractant protein-1 and intercellular adhesion molecule-1 between atherosclerosis and periodontal disease
作者:焦丽宁综述 毕良佳 林江审校
Author:Jiao Lining, Bi Liangjia, Lin Jiang.
收稿日期:2010-08-07 年卷(期)页码:2012,39(1):105-109
期刊名称:国际口腔医学杂志
Journal Name:International Journal of Stomatology
关键字:单核细胞趋化蛋白-1, 细胞间黏附分子-1, 牙周病, 动脉粥样硬化, 牙龈卟啉单胞菌,
Key words:monocyte chemoattractant protein -1, intercellular adhesion molecule -1, periodontal disease, atherosclerosis, Porphyromonas gingivalis,
基金项目:
黑龙江省青年科学基金资助项目(QC2009C103)
中文摘要
以动脉粥样硬化为病理基础的冠心病是目前主要的致死性疾病之一,而牙周病与动脉粥样硬化之间存在着一定的相关性。单核细胞趋化蛋白(MCP)-1 和细胞间黏附分子(ICAM)-1在动脉粥样硬化和牙周病的发生发展中起着重要的作用。本文就MCP-1 和ICAM-1 以及二者与动脉粥样硬化、牙周病间的关系作一综述。
英文摘要
Coronary heart disease on the pathologic foundation of atherosclerosis is one of the fatal diseases now, however, there is an association exists between periodontitis and atherosclerosis. Both monocyte chemoattractant protein(MCP)-1 and intercellular adhesion molecule(ICAM)-1 play important roles in the occurrence and development of atherosclerosis and periodontitis. In this article the relationship between atherosclerosis and periodontitis by means of MCP-1 and ICAM-1 is reviewed.
上一条:抑制核因子-κB 受体活化因子及其配体通路治疗牙周炎的研究进展
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