By anodic oxidation it is possible to fabricate regularly and orderly TiO2 nanotubes. Surface features of TiO2 nanotubes can be affected by the electolyte, the potential and the times of anodic oxidation. TiO2 nanotubes have been observed to promote bone formation, compared with microscale features, and to serve as carriers for drugs such as growth factors, antibacterial agents, and other drugs. This review includes all the aspects above.