Enamel caries is a kind of non-cell reactive lesion, posing the breakdown of the hard tission of teeth. Because tradition treatment of enamel caries will more or less damage the normal tission. At present, it is highly concerned about the new approaches on restoring enamel caries without preparing cavity. For above reasons, this paper will summarize the latest developments on treating enamel caries with non-destructive means, including the way of remineralization and the biomimetic mineralization.