Objective To observe and compare the shear bond strength of different composite resin cement systems to glass infiltrated alumina oxide ceramic. Methods 40 healthy non-carious human molars were selected in the study. The samples were divided into four groups, 10 pieces for each group, including group A(Solobond Plus+Bifix QM), group B(Futurabond DC+Bifix QM), group C(Bifix SE), and group D(Panavia F). All specimens were stored in water at 37 °C for 24 hours. The shear bond strength of four different bonding systems to dentin was tested respectively. The data were statistically analyzed by ANOVA with SAS 6.12. Results Shear bond strength of Panavia F was significantly higher than that of other three groups(P