Dental erosion is the irreversible loss of dental hard tissue by chemical process in the absence of bacteria. Gastroesophageal reflux disease（GERD） is a common gastrointestinal disturbance disease, which considered to be one of the main causes to dental erosion. This review aimed to explore the pathogenesis and mechanism of dental erosion, in addition to explain the clinical manifestation, prevention and treatment of dental erosion. Dental erosion is considered to be one of the most important extra-oesophageal manifestations in patients with GERD. The diagnosis and treatment of dental erosion need to coordinate the department of digestive and the department of stomatology. Early diagnosis of GERD and suppress acid reverse flow through the lifestyle changes and drugs, and prevent dental erosion and further loss of teeth mineral and damage are very important.
