Bioactive ceramics have been widely used in replacing defected hard tissues caused by trauma or disease. When biomaterials are placed in bio-enviroments, various protein molecules will immediately accumulate on material surfaces forming a bioactive layer. Moreover, this protein layer plays an important role in determining the biocompatibility of materials. So this paper briefly reviews the protein adsorption on bioceramics surfaces, including the type of proteins absorbed, methods being used, factors effecting adsorption capacity and methods improving it, providing reference for the surface biological modification of bioactive ceramic materials.
