Objective To explore the method that uses primary tumor contralateral submental island flap to reconstruct tongue and floor of mouth defects. Methods Selected 5 cases that used primary tumor contralateral submental island flap to reconstruct tongue and floor of mouth defects after tumor resection, and observed the clinical efficacy. Results The submental island flap has a long pedicle, which can reach contralateral tongue and floor of mouth if required. All flaps were survived postoperative. Conclusion Contralateral primary tumor submental island flap has many features include: Easy obtaining and high survival rate with minimal donor site morbidity. It does not affect the radical, so it will be an ideal material for repairing tongue and floor of mouth defects.