Objective To investigate caries status of primary and permanent teeth among 6-12-year-old orphans and disabled children in Chengdu and to discuss the appropriate measures of prevention and treatment. Methods A sample of 280 6-12-year-old orphans and disabled children, were selected from 5 special schools in Chengdu. The index of decayed missing filled tooth(DMFT/dmft) was recorded to assess the caries status and analysis with carious related factors. Degree of compliance(DC) and types of disability were used to measure difficulty of preventive and treatment measures. Results The total prevalence rate of dental caries was 59.6%, the total mean DMFT/dmft was 2.16 ±2.63, caries rate with deciduous teeth was 46.4%, the deciduous teeth mean DMFT/dmft was 1.70±2.50, caries rate with permanent teeth was 23.9%, the permanent teeth mean DMFT/dmft was 0.47±1.05. Caries filling ratio of deciduous teeth was 2.1%, caries filling ratio of permanent teeth was 7.6%. The prevalence rate and mean DMFT/dmft between males and females showed no significant(P >0.05). There was a strong correlation between first and second deciduous molar(P