期刊导航

论文摘要

生存蛋白与口腔疾病间的关系

Relationship between survivin and oral diseases

作者:李倩1 潘亚萍1,2

Author:Li Qian1, Pan Yaping1,2.

收稿日期:2012-10-24          年卷(期)页码:2013,40(5):674-677

期刊名称:国际口腔医学杂志

Journal Name:International Journal of Stomatology

关键字:生存蛋白,有丝分裂,程序性细胞死亡,口腔肿瘤,牙周病,唾液腺发育,

Key words:survivin,mitosis,apoptosis,oral cancer,periodontal diseases,salivary gland developmen,

基金项目:

国家自然科学基金资助项目(81070834,81271153)

中文摘要

生存蛋白(survivin)具有调控细胞有丝分裂和抑制程序性细胞死亡的双重功能,可干扰细胞的增殖与程序性死亡,进而影响疾病的发生发展进程。近年来,生存蛋白与口腔疾病间的关系备受瞩目,本文就生存蛋白及其与口腔肿瘤、牙周病和唾液腺发育间的关系等研究进展作一综述。

英文摘要

Survivin, a member of the inhibitor of apoptosis protein family, functions as a regulator of mitosis and cell-death decisions. Survivin affects the initiation and progression of diseases by interfering with cell proliferation and apoptosis. In recent years, the relationship between survivin and oral diseases has attracted considerable research attention. This article focuses on the biological functions of survivin as well as relevant research progress in oral cancer, periodontal diseases, and salivary gland development.

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