Although the interaction of diabetes mellitus and periodontitis was generally accepted, the mechanism is still not identified. Gingival crevicular fluid can reflect the inflammation of the periodontal tissue because it originates from the serum and interstitium. In addition, the simple and noninvasive access of gingival crevicular fluid made it become the hot spots in the researches on the relationship between diabetes mellitus and periodontal diseases in recent years. This article aims to review the researches of gingival crevicular fluid in patients with diabetes mellitus and periodontal diseases.
