From the perspective of patients and orthodontists, accelerating teeth movement is desirable because the treatment duration is very long. The harmless and infection-free low-level laser(LLL) is highly capable of suppressing inflammatory process, reducing pain, and promoting wound healing. Thus, LLL is widely utilized in several different treatments in clinical practice. Researchers have studied the effects of LLL, and found that this method can accelerate alveolar bone remodeling and increase the rate of tooth movement in animals. Several clinical trials have also enhanced the efficiency of LLL in accelerating the velocity of orthodontic tooth movement. In this article, recent experimental and clinical studies on the mechanism through which LLL improves orthodontic tooth movement are reviewed.