Fusobacterium nucleatum, one of the main pathogens causing periodontitis, is detected extremely high in oral and even systemic infectious diseases, and closely related to the clinical anaerobic infections. It indicates significant virulence or pathogenicity through multiple mechanisms to interfere with host defense capabilities and further lead to periodontal destructions. This article describes some important characteristics of Fusobacterium nucleatum, including its biological characteristics, classification, toxicity characteristics, as well as the major biological detection methods, and focuses on the application of polymerase chain reaction technology in the detection of Fusobacterium nucleatum.
