The maxillofacial muscle has an important function in the deformity of the occurrence, development, and correction and a curative effect on maintaining aspects. Skeletal muscles can follow the plasticity of a strong external stimulation change through adaptive remodeling. Orthodontic doctors use this ability to regulate remodeling through orthopedic force. The lateral pterygoid muscle is a masseter muscle that has an important function in the stability of functional orthopedics. In this process, myoblasts are the receptors and effectors of stress stimulation of skeletal muscle remodeling. Studying the mechanics of muscle cells in the signal transduction mechanism is necessary to clarify functional orthopedic skeletal muscle remodeling mechanisms. Therefore, we summarized in this review the various studies on lateral pterygoid muscle myoblast adaptability reconstruction under functional orthopedic, lateral pterygoid muscle and functional orthopedic, and myoblast and functional orthopedic conditions.