期刊导航

论文摘要

舌鳞状细胞癌颈淋巴结转移的特点和评估处理

Lymph node transfer characteristics and clinical assessment and treatment of early tongue squamous cell carcinoma

作者:吴开柳 李思毅 张陈平

Author:Wu Kailiu, Li Siyi, Zhang Chenping

收稿日期:          年卷(期)页码:2015,42(1):119-122

期刊名称:国际口腔医学杂志

Journal Name:International Journal of Stomatology

关键字:舌鳞状细胞癌,淋巴结,颈部转移,

Key words:tongue squamous cell carcinoma,lymph node,neck metastasis,

基金项目:

上海科委生物医药重大科研项目(10DZ1951300)

中文摘要

舌鳞状细胞癌位居口腔癌首位,颈淋巴结转移妨碍其治疗。颈淋巴结转移分为微转移和包膜外转移,前者与肿瘤预后较差相关,后者对患者的生存率影响更大。舌鳞状细胞癌的淋巴结转移多为Ⅰ~Ⅲ区,原发灶浸润深度对颈部隐匿性淋巴转移有较高的预测价值。舌鳞状细胞癌颈淋巴结转移存在着一定的规律性,与其病理分级、神经和血管侵犯、浸润深度等多方面因素相关。颈淋巴结转移的临床评估除需借助B超、CT、磁共振成像、正电子发射断层摄影术等影像学辅助检查技术外,还需借助细胞细针吸取活检和前哨淋巴结活检来确认。迄今有关舌鳞状细胞癌的颈淋巴结处理仍无定论,临床选择上存在着仁者见仁智者见智的现象。目前,舌鳞状细胞癌的颈淋巴结处理主要为颈淋巴结清扫和随访观察两种方式,早发现、早诊断、早治疗仍是解决其问题的主要方式。

英文摘要

Early tongue squamous cell carcinoma has a high incidence rate and easily exhibits lymph node and capsule micrometastases. Studies show that micrometastases indicate a poor prognosis. Hence, clinical evaluation is often difficult. Early diagnosis and treatment are achieved through clinical ultrasound, computerized tomography, magnetic resonance imaging, positron emission tomography, and other auxiliary examinations. However, these methods also have advantages and disadvantages. According to studies, lymph node metastasis in the neck region during early tongue squamous cell carcinoma follows a certain law, which is simultaneously related to several factors. These factors include pathology classification, nerve vascular invasion, and infiltration depth. Accordingly, the management of a clinically node-negative neck in this context remains controversial. The current approach for this case involves an elective neck dissection and a “wait-and-watch policy”. The early detection, diagnosis, and treatment of tongue squamous cell carcinoma remain as problems. This study aims to summarize the preceding data.

上一条:玻璃离子在牙本质再矿化中的作用

关闭

Copyright © 2020四川大学期刊社 版权所有.

地址:成都市一环路南一段24号

邮编:610065