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论文摘要

幽门螺杆菌与口腔疾病的相关性研究进展

Research progress on the correlation between Helicobacter pylori and associated oral disease

作者:孙佳1 法永红2 杨永进2 蔡兴伟2 吕晓宁2

Author:Sun Jia1, Fa Yonghong2, Yang Yongjin2, Cai Xingwei2, Lü Xiaoning2

收稿日期:          年卷(期)页码:2015,42(1):93-96

期刊名称:国际口腔医学杂志

Journal Name:International Journal of Stomatology

关键字:幽门螺杆菌,口腔,疾病,清除,

Key words:Helicobacter pylori,oral,disease,removal,

基金项目:

中文摘要

牙菌斑、唾液以及口腔黏膜等部位均存在着幽门螺杆菌,且以牙菌斑中居多,而龈沟和牙周袋可能是幽门螺杆菌的一个集聚地。幽门螺杆菌不但与牙周炎密切相关,还与口腔黏膜疾病密切相关。幽门螺杆菌可能是牙周炎或促进牙周炎进展的重要细菌,牙周炎也可能是导致幽门螺杆菌根除失败或者感染复发的重要因素。牙周袋较深者的幽门螺杆菌根除率低,龈下幽门螺杆菌可能是胃幽门螺杆菌的再感染源。口腔幽门螺杆菌不仅导致牙周炎等口腔疾病,还会影响幽门螺杆菌的根治。口腔幽门螺杆菌可能是幽门螺杆菌相关性胃肠道疾病复发的始作俑者。三联疗法结合牙周基础治疗较单纯的三联疗法,可以大大地提高幽门螺杆菌的清除率。日常菌斑控制加牙菌斑专业处理更利于对口腔菌斑的控制。本文就幽门螺杆菌,幽门螺杆菌与口腔疾病,口腔幽门螺杆菌感染的清除等研究进展作一综述。

英文摘要

Helicobacter pylori(H.pylori) can remain in dental plaques, saliva, oral mucosa, and other parts of the oral cavity. H.pylori is mainly found in dental plaques, the gingival sulcus, and periodontal pockets. It is closely associated with not only periodontitisbut also oral mucosal diseases. Although H.pylori promotes or causes periodontitis, interestingly, it can also be eliminated through the infection caused byperiodontitis. However, subgingival H.pylori may be a source of H.pylori re-infection. The elimination rate of H.pyloriis lower in patients with deep periodontal pockets than in those with shallow pockets. H.pylori re-infection not only leads to oral diseases, such asperiodontitis, but also affects H.pylori treatment. Oral H.pylori may be related to recurrence of gastrointestinal diseases. Triple therapy combined with periodontal treatment can greatly improve the removal rate of H.pylori compared with simple triple therapy only. Daily plaque control combined with professional handling is more strategic for oral plaque control. H.pylori, its associated oral diseases, and treatment methods are reviewed in this paper.

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