Objective This experiment aimed to identifythe effects of the coating formed on the surface of porous titanium after alkali treatment on alkaline phosphate(ALP) activity of human periodontal ligament cells(hPDLCs). Methods Porous titanium was made by loosening the sintering. The alkali treatment group was soaked in Na0H and then in simulated body fluid. The equal hPDLCs were co-cultured with the alkali treatment group and the control group The ALP activity of hPDLCs cultured on the titanium surface was assessed at day 1, 2, 3, and 4. Results The alkali treatment group had better biocompatibility than the control group. Conclusion Porous titanium after alkali treatment may promote mineralization ability of hPDLCs.
