Objective To identify the independent risk factors of atrophic glossitis and the influence factors of atrophic glossitis degree in primary Sjögren’s syndrome(pSS) patients. Methods The clinical data of 36 cases of pSS patients were collected and taked the tongue back photos, graded the level of the atrophy of tongue papillae on the back of the tongue. Clinical manifestation, subjective symptoms and extractable nuclear antigens(ENA) spectrum were compared between the pSS patients with atrophic glossitis and without atrophic glossitis. The risk factors that may cause atrophic glossitis were analyzed by univariate and multivariable Logistic regression analysis and chi-square test. Results There were 18 patients in 36 pSS patients(50%) with atrophic glossitis. Age>65, and Ro-52 positive were the risk factors of atrophic glossitis occurred in patients with pSS. Age>65 affected the incidence of atrophic glossitis degree. There was a statistically difference between groups(P
