Objective This study was conducted to evaluate the clinical effect of inlay crowns made from IPS e.max press ceramic on short crown molar teeth. Methods A total of 85 short crown molar teeth, which received completed root canal therapy, were restored with IPS e.max press ceramic inlay crowns and were assessed after 36 months. Results A total of 82 restorations displayed good results, such as favorable retention, perfect fitness of the edge, and good masticatory function. During a follow up period of 36 months, no secondary caries and periodontal diseases were detected. The success rate of this restoration was high(96.47%). Conclusion IPS e.max press ceramic inlay crowns have good retention effects and high success rate on short crown molar teeth. Thus, they are worth promoting.