A superogranism consisting of eukaryotic cells and microbial communities that symbiose in the human body. Mouth, as the entrance of microorganisms into human body, harbors one of the most complex ecosystem and microbiome of the human. The normal colonization and balance of the oral microbial community are essential for maintaining oral and systematic health. The oral microbiome varies most during childhood, when contact with external microbes is highest. In the first few months of life, the major influences on the oral microbial succession are from person-to-person transmission, mode of feeding, and microbial cross-talk. In the edentulous stage, microbial adhersion occurs only to the oral mucosa. With the eruption of the first teeth, a new ecological event takes place in the oral environment, with the emergence of new adhesion surfaces. So this happens when permanent teeth erupt.
