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论文摘要

HIPPO通路在口腔系统发育和疾病中的研究进展

Research progress on the role of HIPPO pathway in the development of the oral system and diseases

作者:郝旭蕾 梁新华

Author:Hao Xulei, Liang Xinhua

收稿日期:2015-06-26          年卷(期)页码:2016,43(1):52-

期刊名称:国际口腔医学杂志

Journal Name:International Journal of Stomatology

关键字:HIPPO信号通路,口腔,发育,

Key words:HIPPO pathway,oral,development,

基金项目:

国家自然科学基金(81361120399)

中文摘要

HIPPO信号传导通路是一个高度保守的信号通路,其对细胞的增殖、凋亡和器官发育都有重要的调控作用。研究表明,此通路参与人类生长发育的过程,并与多种疾病密切相关。本文综述HIPPO通路在口腔系统相关领域中的最新进展,概述HIPPO通路对口腔系统发育、疾病的影响,以求为日后口腔临床疾病的研究和治疗提供新的思路和策略。

英文摘要

HIPPO signaling pathway is a highly conservative signaling pathway involved in the regulation of cell proliferation, apoptosis, and organ sizes. This pathway is involved in human growth and development and is closely related to the occurrence of various diseases. Herein, we review the recent progress of research on HIPPO pathway in the dental field and the influence of HIPPO pathway on the development of the oral system and diseases. This review can provide new ideas and strategies for further investigations and treatment of oral diseasesh.

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