Objective This study aimed to assess the diagnostic efficacy of pantomography in the screening of mandibular invasion by oral cancers. Methods Seven electronic databases, including MEDLINE, EMBASE, MEDION, and CBM, were searched electronically on October 25, 2014. Hand-searching was also performed. QUADAS-2 was used by two independent reviewers to assess the methodological quality, and data extraction of included studies was delivered by two reviewers in duplicate. Meta-analysis was conductedvia MetaDisc 1.4. Results A total of 12 studies involving 528 participants were included. Sevenstudies were prospective, 2 had high risk of bias, and the rest had unclear risk of bias. Meta-analysis showed that when screening mandibular invasion, pantomography had a pooled sensitivity of 0.761, pooled specificity of 0.828, area under curve of 0.884, and Q* of 0.814. Conclusion Pantomography is a good tool for oral cancer mandibular invasion screening. More studies on mandible medullary invasion diagnosed by pantomography should be conducted.
