Objective To evaluate the success rates of IPS Empress ceramic veneers in esthetic restoration of anterior teeth with different veneer designs. Methods 124 anterior teeth in 41 patients were collected and prepared by labial overlap (type I), incisive edge overlap (type L) and finishing lines extended proximally (type U). The veneers’ integrity, fracture, color match and the marginal situation were evaluated at 1 week, 6 months and 12 months. Results For type I, 1 failure was found at 12-month follow-up. For type L, 2 failed at 6-month follow-up and 1 failure at 12-month followup. For type U, 1 failed at 6-month follow-up. There was no significant differences in success rates among three types of veneers. Conclusion Each type of IPS Empress ceramic veneer could get excellent clinical effectiveness.