The genusVeillonellais a member of the normal oral flora and is highly abundant in the human oral cavity.Veillonellautilizes lactate, which ameliorates the caries process. However, Resultsofin vitrostudies and rat model systems are ambiguous. With the development of human oral microbiome research, several studies reported that the frequency ofVeillonellain caries-activated individuals is higher than that in caries-free ones, and the distribution ofVeillonellais highly related to some cariogenicStreptococcusspecies.Veillonellafacilitates the action of some cariogenicStreptococcusspecies, such asStreptococcus mutansin caries development. These findings create new focus on the genusVeillonellaas a factor relating to caries. This paper provides a review on the distribution ofVeillonellain human oral cavity, the relationship betweenVeillonellaand caries, and the relationship betweenVeillonellaandStreptococcusspecies related to caries.