期刊导航

论文摘要

外泌体与口腔疾病关系的研究进展

Research progress on exosomes and oral diseases

作者:吴佳梦, 王效英

Author:Wu Jiameng, Wang Xiaoying.

收稿日期:2016-10-12          年卷(期)页码:2017,44(3):336-339

期刊名称:国际口腔医学杂志

Journal Name:International Journal of Stomatology

关键字:外泌体, 口腔疾病, 生物标志物,

Key words:exosome, oral disease, biomarker,

基金项目:

中文摘要

外泌体是由各种类型的细胞分泌的多形性囊泡样小体,其中含有蛋白质和RNA等多种成分,具有抗肿瘤免疫、促血管新生等生理功能,并且与口腔疾病密切相关。外泌体可作为口腔癌、口腔黏膜病、唾液腺疾病等口腔疾病诊断的生物标志物,还有作为口腔癌候选抗癌疫苗的可能。本文主要就外泌体及其与口腔疾病的关系作一综述。

英文摘要

Exosomes secreted by various types of cells are small vesicular bodies that contain many types of proteins and RNAs. They have multiple functions, such as anti-tumor immunity and angiogenesis. Their possible use as oral disease biomarkers and vaccine candidates was also discussed. This review presents recent advances in exosomes and the relationship with oral diseases.

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