Denture stomatitis is a common disorder affecting denture wearers. The typical symptom of denture stomatitis is characterized as inflammation and erythema of the oral mucosal areas covered by the denture. However, the etiology of denture stomatitis is not completely understood. A large number of surveys have shown a strong link betweenCandida albicansand denture stomatitis. Basically, theC. albicanspathogenicity included different factors: adhesins, secreted enzymes, and the diversity of morphological. The virulence factors involved in the pathogenic procedures are usually mediated by one or more signal pathways of correlated genes. The aim of this paper is to review current understanding on the roles ofC. albicansand its virulence factors during the denture stomatitis development, as well as the reactions of host cells when infected byC. albicans.
