Total maxillectomy is always necessary for the surgical treatment of maxillary and maxillary sinus tumor. The resulting orbital floor defect may cause serious complications, such as diplopia, enophthalmos, and ectropion, which lead to both severe functional problems and periorbital deformities seriously affecting the patients’ physical and mental health and quality of life. A variety of methods have been developed to reconstruct orbital floor defects, including nonvascularized and vascularized bone grafts, soft-tissue flaps in conjunction with maxillofacial prostheses, and biological materials. In this article, various methods for orbital floor reconstruction after total maxillectomy are summarized, including the advantages and disadvantages.