Objective This study monitored postoperatively the local skin temperature of patients after applying cold compress, either continuously or intermittently, following oral and maxillofacial surgery to provide sound basis for clinical nursing. Methods By using non-contact infrared forehead thermometer, we monitored the local skin temperature of 40 eligible patients by applying cold compress immediately and 0.5, 1.0, 1.5, 2.0, 2.5, and 3.0 h after maxillofacial surgery. Results After cold compress reduced the skin temperature of the patients to above 30 °C, the skin temperature tends to rise with time. Conclusion The cold compress may be extended appropriately when necessary. Non-stop cold compress for 24 h may be applied, although the ice packs must be replaced every1-2 h.