The surgical removal of impacted third molars remains the most common procedure performed by oral and maxillofacial surgeons. Considering the total number of patients, the complication is generally low, but the sum is rather high. Local infection is among the most common complications of third molar removal. The efficacy of antibiotics in reducing the frequency of infection and the advantages and disadvantages of antibiotic use are still questionable. This article provides a comprehensive review of available data on using antibiotic prophylaxis in impacted third molar surgery.
