Objective The aim of this study was to observe the clinical effect of an in-office desensitizing polishing paste containing 8% arginine and calcium carbonate on the treatment of root-dentin hypersensitivity after subgingival scaling with ultrasonic instrument. Methods This was a randomized double-blind controlled, clinical study. The 82 subjects who presented at least two hypersensitive teeth either front teeth or premolars with an air blast hypersensitivity scores of 2 or 3 according to schiff cold air senditivity scale after subgingival scaling with ultrasonic instrument in one week were randomly stratified into two groups. 40 subjects in test group were treated with an in-office desensitizing polising paste containing 8% arginine and calcium carbonate. 42 subjects in control group were treated with the proxyt polishing paste. The effect of desensitization was evaluated immediately after treatment. Results Eighty-two subjects participated and completed in this treatment. The average air blast hypersensitivity score of test paste was 1.34±0.48. The average air blast hypersensitivity score of control paste was 2.24±0.55. There was significant difference between control and test group(P
