Patients with severely atrophied maxilla cannot provide bone tissue for implant anchorage because of the insufficient height and width of their residual alveolar ridges. Many approaches have been suggested to solve this problem, such as autogenous or allogeneic bone grafting; bone grafting with sinus floor augmentation; and the use of short implants, pterygomaxillary implants, zygomatic implants, or removable prostheses. The use of zygomatic implants is an effective method that can avoid bone grafting and adopt immediate rehabilitation. These advantages ideally solve problems on mastication, pronunciation, and appearance in a short time. As a result, scholars have increasingly favored this method over other techniques. In recent years, the design and the surgical techniques of zygomatic implant application have developed rapidly. This article aims to review the related anatomy, general guidelines, surgical techniques, immediate rehabilitation, and the prospects related to zygomatic implant application.