Root resorption is a common complication of orthodontic treatment whose factors are very complicated. The processe of root resorption is similar to bone resorption. The cementoclast plays a main role in this process, and it is similar to the shape and function of osteoclasts. Osteoclastic protein-tyrosine phosphatase(PTP-oc) is mainly expressed in osteoclasts, and has a positive regulatory effect on osteoclasts. In this paper, the mechanism of PTP-oc is discussed, which provides a reference for the prevention and treatment of root resorption.
