茸怡露口服液的抗辐射及免疫调节研究
Study on the radioresistance and immunoregulation effects of Rongyilu oral liquid
作者:徐艺箐;谭辉;马超英;耿耘;王兴;陈慧泼;马小俊;
Author:
收稿日期: 年卷(期)页码:2019,34(01):-52-54
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:茸怡露口服液;抗辐射;免疫调节;外周血白细胞计数;紫外分光光度计法;骨髓细胞;淋巴细胞计数;脾脏指数;胸腺指数
Key words:
基金项目:
中文摘要
目的探究茸怡露口服液是否具有抗辐射和免疫调节的功能。方法用60Coγ射线照射小鼠,测定小鼠经茸怡露口服液治疗前后外周血白细胞的数量,采用紫外分光光度计法测定治疗后骨髓细胞中DNA的含量;通过注射氢化可的松制备小鼠免疫缺陷模型,测定治疗后小鼠外周血淋巴细胞的转化率,并计算脾脏、胸腺指数。结果茸怡露口服液能抑制被辐射小鼠外周血白细胞数量的降低、骨髓细胞中DNA含量的减少,能显著升高小鼠外周血淋巴细胞的转化率,提高脾脏、胸腺指数。结论茸怡露口服液具有抗辐射和免疫调节的功能。
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