复方甘草酸苷治疗新型冠状病毒肺炎的可行性分析
Feasibility analysis of Compounds glycyrrhizin in the treatment of COVID-19
作者：
Author：
收稿日期： 年卷（期）页码：2020,35(03):-342-346
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：新型冠状病毒肺炎;新型冠状病毒;严重急性呼吸综合征;甘草酸苷;抗病毒;可行性分析
Key words：
基金项目：
中文摘要
临床上大都采用对症治疗的方式治疗新型冠状病毒肺炎(COVID-19),对于新型冠状病毒尚无特效抑制药物。现通过对既往复方甘草酸苷用于严重急性呼吸综合征(SARS)治疗的有效性和安全性的总结,以期为复方甘草酸苷抗击新型冠状病毒肺炎提供理论依据。
参考文献
[1] 中华人民共和国国家卫生健康委员会.截至3月8日24时新型冠状病毒肺炎疫情最新情况[EB/OL].http://www.nhc.gov.cn/xcs/yqfkdt/202003/f2c83db9f73d4be5be 0dc96af731813c.shtml.
[2] Chen H,Du Q.Potential natural compounds for preventing 2019-nCoV infection[J/OL].2020.https://www.preprints.org/manuscript/202001.0358/v1.
[3] Li J,Cao H,Liu P,et al.Glycyrrhizic acid in the treatment of liver diseases:Literature review[J].Biomed Res Int,2014.DOI:10.1155/2014/872139.
[4] Xu X,Chen P,Wang J,et al.Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission[J].Sci China Life Sci,2020.DOI:10.1007/s11427-020-1637-5.
[5] 林晓兰,崔琪,王育琴,等.复方甘草酸苷对SARS患者激素撤药综合征的影响[J].中国药房,2004,15(6):37-39.
[6] Fan Z,Chen L,Li J,et al.Clinical features of COVID-19-related liver damage[J/OL].2020.https://doi.org/10.1101/2020.02.26.20026971.
[7] Cinatl J,Morgenstern B,Bauer G,et al.Glycyrrhizin,an active component of liquorice roots,and replication of SARS-associated coronavirus[J].Lancet,2003,361(9374):2045-2046.
[8] Abe N,Ebina T,Ishida N.Interferon induction by glycyrrhizin and glycyrrhetinic acid in mice[J].Microbiol Immunol,1982,26(6):535-539.
[9] 汪学功,高伟良.NO抗病毒效应[J].微生物学免疫学进展,1997,25(3):81-83.
[10] Hoever G,Baltina L,Michaelis M,et al.Antiviral activity of glycyrrhizic acid derivatives against SARS-coronavirus[J].J Med Chem,2005,48(4):1256-1259.
[11] 方炳虎,邱灵才,陈建新,等.甘草主要成分抗H9N2亚型流感病毒作用研究[J].广东农业科学,2007,26(3):66-69.
[12] Kobayashi M,Davis SM,Utsunomiya T,et al.Antiviral effect of gingyo-san,a traditional Chinese herbal medicine,on influenza A2 virus infection in mice[J].Am J Chin Med,1999,27(1):53-62.
[13] Li Z,Zhao Y,Lin W,et al.Rapid screening and identification of active ingredients in licorice extract interacting with V3 loop region of HIV-1 gp120 using ACE and CE-MS[J].J Pharmaceut Biomed,2015,111:28-35.
[14] Crance JM,Scaramozzino N,Jouan A,et al.Interferon,ribavirin,6-azauridine and glycyrrhizin:Antiviral compounds active against pathogenic flaviviruses[J].Antivir Res,2003,58(1):73-79.
[15] 赵艳丽,王微,王松.阿昔洛韦与甘草酸苷体外抗HSV-1活性比较[J].黑龙江医药,2013,26(1):42-44.
[16] Wu Y.Naturally derived anti-hepatitis B virus agents and their mechanism of action[J].World J Gastroenterol,2016,22(1):188-204.
[17] 张美玲.复方甘草酸苷注射液不良反应文献分析[J].中国新药杂志,2011,20(3):289-292.
[18] 蔡玲,张泰昌,张玫.复方甘草甜素治疗严重急性呼吸综合征的疗效[J].中国新药杂志,2004,13(9):842-845.
[19] 杜普,唐中权,冯铁柱,等.大剂量甘草甜素治疗严重急性呼吸综合征31例[J].内蒙古医学杂志,2004,36(1):27-28.
[20] 吴赤红,徐小元,陆海英,等.复方甘草酸苷治疗传染性非典型肺炎患者胸部X线表现分析[J].中国药房,2004,15(1):40-42.
[21] 陈宇萍,刘新记,刘克锋,等.复方甘草酸苷注射液治疗传染性非典型肺炎的临床观察[J].中国药房,2004,15(5):38-39.
[22] 陆海英,娜霍,王广发,等.复方甘草酸苷治疗传染性非典型肺炎(SARS)的临床研究[J].药物与临床,2003,14(10):610-611.
[23] 穆凯.复方甘草酸苷治疗肝病的临床效果及安全性探析[J].首都食品与医药,2019,26(17):62.
[24] 巢锋金.复方甘草酸苷注射液联合丹参粉针治疗慢性乙型肝炎肝纤维化的临床疗效及其安全性[J].临床合理用药杂志,2019,12(30):11-12.
[25] 袁元,李静.复方甘草酸苷联合替诺福韦酯对慢性乙型肝炎患者的临床疗效[J].中成药,2019,41(10):2544-2546.
[26] Zhou P,Yang X,Wang X,et al.A pneumonia outbreak associated with a new coronavirus of probable bat origin[J].Nature,2020,579(7798):270-273.
[27] 周外民,赵富明,李榜龙,等.甘草酸二胺在普通型新型冠状病毒肺炎患者治疗中的临床价值[J].病毒学报,2020,36(2):160-164.
下一条：新型冠状病毒肺炎相关循环系统血栓防治的药学监护
【关闭】
