溴化金催化醛及芳香胺串联反应合成2,3-二取代喹啉
AuBr_3-catalyzed tandem reaction of aldehydes and arylamines to synthesize 2,3-disubstituted quinolines
作者：马俊雨;郭娜;成明;杜锋田;姬建新;张强;
Author：
收稿日期： 年卷（期）页码：2015,30(05):-525-527
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：溴化金;催化;串联反应;醛;芳香胺;合成;喹啉
Key words：
基金项目：国家自然科学基金资助项目(批准号:21172213,2140020768)
中文摘要
目的建立简单、快捷合成喹啉类化合物的方法。方法以溴化金为催化剂,THF为溶剂,在60℃下,催化芳香胺和脂肪醛合成喹啉类化合物。结果和讨论合成了一系列2,3-二取代喹啉类化合物,结构经1HNMR、13CNMR和HR-MS表征。该反应具有操作简便、原料易得、条件温和、时间短等优点。
英文摘要
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