摘要:As a key mediator of normal physiological angiogenesis, vascular endothelial growth factor(VEGF)has been regarded as an emancipator to plastic surgeon, and yet a misfortune to oncology surgeon, due to its singular biological effect. Therefore in some clinical cases, especially for some malignant tumor patients having endured radical surgery and being craving for a reconstructive surgery, VEGF plays a role full of paradoxes. To make a clinical balance, we should find a point to inhibit tumor cell from utilizing VEGF and make a permission to normal tissues to employ it.
关键词:vascular endothelial growth factor,malignanttumor,reconstructivesurgery
Abstract:As a key mediator of normal physiological angiogenesis, vascular endothelial growth factor(VEGF)has been regarded as an emancipator to plastic surgeon, and yet a misfortune to oncology surgeon, due to its singular biological effect. Therefore in some clinical cases, especially for some malignant tumor patients having endured radical surgery and being craving for a reconstructive surgery, VEGF plays a role full of paradoxes. To make a clinical balance, we should find a point to inhibit tumor cell from utilizing VEGF and make a permission to normal tissues to employ it.
麻鹏,刘春丽.Role of vascular endothelial growth factor in r econstructive surgery after surgi[J]. 国际口腔医学杂志, 2008, 35(3): 242-242~245.
MA Peng, LIU Chun-li.Role of vascular endothelial growth factor in r econstructive surgery after surgi[J]. Inter J Stomatol, 2008, 35(3): 242-242~245.