Streptococcus mutans（S. mutans） can produce dental plaque biofilm , which is closely related to dental caries. With the developm ent of m odern stom atology and molecular biology， there are more and more studies on genes related to dental plaque biofilm . As a result, lots of the genes are found, m ainly including those involved in adhesion, quorum-sensing signal system and so on. Studying these genes can further ensure the m echanism s about form ation of dental caries, and has also explored new way to prevent dental caries. In this article, the studies on gene m utation related to dental plaque biofilm of S. m utans in recent years have been reviewed.
